Metastability
When a flip-flop can't decide.
Violate a flip-flop's setup or hold window and its output can hover between 0 and 1 for an unbounded time before randomly resolving — that's metastability. It can't be prevented when sampling truly asynchronous signals; it can only be given time to resolve.
The standard cure is the two-flop synchronizer: the first flop may go metastable, the second samples it a full cycle later, by which time the probability of still-undecided is astronomically small (MTBF measured in years). The CDC generator produces properly attributed synchronizers, and every CDC structure is built on this idea.